Lymphology. 2011 Dec;44(4):178-82.
Lymphedema treatment decreases pain intensity in lipedema.
Szolnoky G, Varga E, Varga M, Tuczai M, Dósa-Rácz E, Kemény L.

Lipedema is a disproportional obesity featuring light pressure-induced or spontaneous pain. Thirty-eight women with lipedema were enrolled in the study with 19 patients undergoing treatment and 19 serving as the control group using exclusively moisturizers. Treatment consisted of once daily manual lymph drainage (MLD), intermittent pneumatic compression (IPC), and multilayered short-stretch bandaging performed throughout a 5-day course. Pain was evaluated with a 10-item questionnaire, a pain rating scale (PRS), and the Wong-Baker Faces scale. Treatment resulted in a significant reduction of pain with a decrease in mean scores of all three measures. In the control group, only PRS showed significant decrease.

RESULTS: This treatment regimen reduced pain intensity, leg volume and capillary fragility  in patients with lipedema.