Arch Surg.  1985 Oct;120(10):1116-9.
Sequential pneumatic compression for lymphedema. A controlled trial.
Richmand DM, O’Donnell TF Jr, Zelikovski A.

A prospective study of seven patients with upper extremity and 18 patients with lower extremity lymphedema was performed. Treatment was applied for 24 hours in an inpatient setting. All extremities showed a decrease in circumferential measurements. Lower extremity leg volume was reduced by 45%. No elevation in serum muscle enzyme levels was noted.

RESULTS: The Lympha Press® reduced lymphedema rapidly and safely. Follow up at three to six months after treatment showed that patients who were compliant with use of static compression garments maintained retention of 50% or more of their reduction.